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SCANDINAVIAN JOURNAL OF IMMUNOLOGY
SCAND J IMMUNOL
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出版周期: Monthly
出版ISSN: 0300-9475
通讯方式: WILEY-BLACKWELL PUBLISHING, INC, COMMERCE PLACE, 350 MAIN ST, MALDEN, USA, MA, 02148
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医药科学(1)
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审稿速度: 平均 1 个月的审稿周期(非官方数据)
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#1 作者:yyc12596 (联系作者 | 作者点评过的期刊)   时间:2013-10-11 02:00 纠错举报

投稿刚好一个月,收到拒稿信。个人感觉审稿人很敷衍,提的审稿意见简直牛头不对马嘴。审稿速度还可以,一个月就拒稿,不算拖。

Dear XXX:

I write you in regards to manuscript # SJI-13-237 entitled "XXXXXXXX" which you submitted to the Scandinavian Journal of Immunology.

In view of the criticisms of the reviewer(s) found at the bottom of this letter, and a discussion among the Editors, your manuscript can unfortunately not be published in the Scandinavian Journal of Immunology. In part this is based on scientific quality, but also for the competition of space in this journal.

However, I think your paper is a candidate for potential publication in Immunity, Inflammation and Disease, a peer-reviewed, open access, interdisciplinary journal providing rapid publication of high-quality research in immunology. To learn more about Immunity, Inflammation and Disease, please go to www.immunityinflammationdisease.com/info. At this site you can automatically transfer your paper and any related reviews to Immunity, Inflammation and Disease. You do not need to revise or reformat your paper before transferring it.

Thank you for considering the Scandinavian Journal of Immunology for the publication of your research. I hope the outcome of this specific submission will not discourage you from the submission of future manuscripts.

Sincerely,
Prof. Peter Garred
Associate Editor, Scandinavian Journal of Immunology
garred@post5.tele.dk


Reviewer(s)' Comments to Author:

Reviewer: 1
Comments to the Author
This is a study of a relatively large group of Chinese XXX patient adressing genetics and cytokine profiles. The cytokine study is base on previous studies from the same group, indicating that XXX has a cytokine profile considered specific for XXX. In the present study the authors find significant elevated levels of certain cytokines compared to healthy controls with no difference between patients exhibiting mutations in genes that are established as diagnostic for XXX, compared to patients not exhibiting any of these mutations.

Although this finding may be of some interest the rationale for adressing this question is not well explained. To my knowledge there is no difference in the clinical presentation of the two examined subgruops of XXX studied (+/- proven genedefects), and the authors do not present evidence supporting this. Further no difference in the levels of inflammatory markers that are established as clinical holdmarks for XXX has beeen shown in this study. The data might have been of greater interest if associations between established disease parameters and the applied cytokine profiles were presented. To that comes that it may be questioned whether it is justified to claim that the used cytokine profile is actually ”specific” for XXX. A similar profile with elevatedXXX may be seen in other diagnostic entities characterised by hyperinflammation or infection.
The genetics show a number of mutations not previously reported, but these could be publiced in a more concise form.
The objective and the hypothesis of the study is not clearly stated in the introduction. In all the scientific background for this study appears rather weak.
The abstract is not clear and it is partially not compatible with the findings of the study. Fx it says that study confirms the usefulness of the cytokine profile – evidence for that is not stated – the clinical problem is to differentiate between other conditions with fever, inflammation or infection – and not to differentiate towards healthy individuals.

Minor:

Units on y-axis are missing
Some cytokines are detected at very low levels around 5 pg/ml – but the detection limits of the assays are not stated and the variability is not given.
There are several examples of poor english that needs re-wording, in particular in the abstract.
Fx p. 1 43: in the world; l. 52: is probably served
p. 2. l. 29: hypercytokinaemia
p. 4. l 22: any two of the
p.5 l. 50: of secondary

研究方向: 医药科学

投稿周期: 约1个月

录用情况: 已投被拒

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